U-Skin™

U-Skin™

Substantiate the lasting and mattifying effects of your cosmetics by evaluating sebum/sweat interactions.

Substantiate the lasting and mattifying effects of your cosmetics by evaluating sebum/sweat interactions.

Sweat and sebum resistance testing for cosmetics - U-Skin

Understanding the U-Skin ™ technology

Understanding the U-Skin™ technology

U-Skin™ is a cutting-edge in vitro technology designed to accurately test and substantiate the efficacy of makeup and skincare products.

By simulating human sweat, sebum, lacrimal fluid, and saliva excretion, U-Skin™ allows for precise and rapid evaluation of a product’s
performance in just two hours, ensuring faster time-to-market and enhanced formulation confidence.

Key Benefits of U-Skin™

  • Sweat AND sebum simulation: U-Skin™ utilizes a synthetic polymeric skin with human-like pore density to replicate real skin conditions, simulating sweat, sebum, and even lacrimal and saliva fluids for testing products like lipsticks.

  • Accurate results in 2 hours: U-Skin™ delivers fast and reliable data, reducing the need for lengthy in vivo testing and accelerating product development.
  • Product characterization and marketing claims: U-Skin™ helps evaluate the sebo-resistance, and sweat-resistance of makeup products, ensuring superior long-lasting and mattifying effects.
  • Illustrative, objective and quantifiable data: With U-Skin™, advanced imaging systems measure color and brightness variations, providing objective data to support cosmetic claims such as “long-lasting” and “mattifying.”
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We see the surface of U-Skin™, showcasing a polymer that is fully biomimetic. The material used in this polymer closely mimics the properties of human skin, ensuring realistic testing conditions for cosmetic products.

Sweat and sebum resistance testing for cosmetics - U-Skin
Sweat and sebum resistance testing for cosmetics - U-Skin

A technology correlated to in vivo

A technology correlated to in vivo

U-Skin™ combines a microfluidic system with a synthetic skin model, allowing controlled fluidic flow through pores to test product interactions with sweat and, sebum. This innovative setup predicts in vivo results, offering a reliable correlation between laboratory testing and real-world application.

Over the many tests that were conducted, Microfactory proved the in vivo / in vitro correlation of U-Skin™ with the CIDP, with regard to color variation for three foundations

For each product

  • 12 women selected
  • Clinical scoring by makeup professionals
  • Front view images using the VISIA-CR®
  • Image analysis by Newtone
  • 4 timepoints (T0, Timmediate, T12h, T24h)

Image of a volunteer

Image of U-Skin™

For each product

  • 3 tests = triplicate for accuracy
  • Colored and polarized images using U-Skin™ imaging system
  • Continuous analysis
Sweat and sebum resistance testing for cosmetics - U-Skin

U-Skin™ predicts in vivo results and marketing claims only 2h thanks to steeper product discrimination

Need to conduct a study?

Need to conduct a study?